Symptoms of Multiple Myeloma

Symptoms in patients with multiple myeloma in addition to anemia is infection, bleeding, bone pain can occur (most severe fractures), proteinuria (uremia), other symptoms, namely blood hypercoagulability or venous thrombosis.

Multiple myeloma diagnosis rate reached 40% -50%, the most common cause of diagnosis are:

1 infection: patients are susceptible to respiratory infections and urinary tract infections, delay can cause death. Therefore, in elderly patients with persistent infection, do not have to be limited to anti-infective therapy, at the same time anti-infective therapy can search for the primary cause. If the patient has bone pain, anemia, bleeding and other symptoms should consider the possibility of this disease.

2 Anemia in patients with multiple myeloma usually depressed bone marrow pressure can cause anemia.

3 Symptoms of bone: bone pain, local mass, fractures and even paralysis.

4. hypercalcemia: that seen with symptoms such as vomiting, fatigue, confusion, polyuria, constipation, and other symptoms.

5. hyperviscosity: usually seen with symptoms of dizziness, vertigo, tinnitus, can suddenly disturbed consciousness, numbness of the fingers, heart disorders, chronic heart failure and other symptoms.

6 Impaired renal function: the time of diagnosis, patients often accompanied by renal insufficiency.

Diagnosis of Multiple Myeloma

Clinical findings, almost two-thirds of patients in the early diagnosis and treatment when diagnosed with advanced, many patients because of the wrong diagnosis could be wrong. Expert of Modern Cancer Hospital Guangzhou advise patients if experiencing bone pain, anemia, kidney abnormalities, recurrent infections and other symptoms, patients are advised to immediately perform hematology treatment so that early detection can be timely and effective in controlling the progression of the disease.

Index of suspicion of multiple myeloma patients is quite high, immunoglobulin should be timely, urine Bence Jones protein, X-ray radiography and bone marrow examination. X-ray examination with lots of help diagnose the disease, can be found in a variety of sizes with a circular area some bone damage (especially the bones of the skull, ribs, spine, pelvis), if necessary a CT-scan or MRI. MRI examinations can help to find whether there is compression of the bone marrow; CT scan can help show extramedullary lesion. Sometimes, only the X-ray find a wide variety of multiple myeloma as osteoporosis. Examination of multiple myeloma requires a multi-site examination of puncture or bone marrow biopsy.